1. Introduction
Silicon dioxide is an inorganic compound. Its chemical formula is SiO2. It has characteristics of good fluidity, high purity, small particle size and large specific surface area. At the same time, the silanol groups distributed on the surface endow silicon dioxide good adsorption. In pharmaceutical field, it is used as pharmaceutical excipient, due to some advantages of silicion dioxide, and its application in pharmaceutical production has received more and more attention.
2. Advantages of silicon dioxide as pharmaceutical excipient
① It is a single inorganic compound, with stable chemical and physical properties. It will not react with the main ingredients during drug production, thereby ensuring the efficacy of drugs.
② It has good water absorption and fluidity, which can shorten the disintegration time of the drug.
③ It does not contain starch or protein, so the drug will not go moldy and become ineffective.
④ As lubricant and glidant, silicon dioxide can increase the sliding property of the particles, make the density distribution of the tablets uniform, and ensure the integrity of the tablets.
⑤ As a carrier for drug delivery, silicon dioxide can improve the stability and bioavailability of drugs, due to its strong adsorption, hydrophilicity and biocompatibility. This provides a broader space for the development of new drugs.
3. Summary
From the above, it can be seen that silicon dioxide has many advantages as pharmaceutical excipient, due to its unique characteristics. In practical applications, in order to make silicon dioxide play a better role and achieve required particle size, it usually needs to be ground and classified.
Qingdao Epic Powder Machinery Co., Ltd is a manufacturer specializing in the production of powder machinery. The ball mill and air classifier produced by our company are suitable for grinding and classifying silicon dioxide, with good quality and favorable price. They are ideal choices for you.
Our main products include:
– Mills: ball mill, air classifier mill(ACM), roller mill, jet mill, turbo mill and impact mill, etc.
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– Surface coating modifiers: pin-mill modifier, turbo-mill modifier and three-roller-mill modifier, etc.
– Auxiliary equipment: control cabinet, dust collector and bucket elevator, etc.
– Customers can customize products according to actual needs. One customer, one design.
If you are interested in ball mill and air classifier or other products from Qingdao Epic, contact our staff directly, we are always at your service.
